Anti-HAND1 (Heart And Neural Crest Derivatives Expressed Protein 1, Hxt, Thing1, eHand, bHLHa27, Class A basic helix-loop-helix protein 27, Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) Polyclonal Antibody

Heart- and neural crest derivatives-expressed protein 1 is protein belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation.Plays an essential role in early trophoblast differentiation and in cardiac morphogenesis. In the adult, could be required for ongoing expression of cardiac-specific genes.||Applications: |Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested.||Recommended Dilution:|ELISA: 1:100-1:5000 |Western Blot: 1:50-400|Immunohistochemistry (frozen): 1:50-500 |Immunohistochemistry (paraffin): 1:10-100 |Immunocytochemistry: 1:50-500 |Optimal dilutions to be determined by the researcher.||Storage and Stability:|May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.