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C2 Ceramide [3102-57-6]
Referência 10-1181-5mg
Tamanho : 5mg
Marca : Focus Biomolecules
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Telefone : +1 850 650 7790
C2 Ceramide | Cell permeable ceramide
CAS:
3102-57-6
Catalog Number:
10-1181
Activity:
Cell permeable ceramide
Chemical Name:
N-Acetyl-D-erythro-sphingosine
Molecular Weight:
341.54
Molecular Formula:
C20H39NO3
Solubility:
Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 25 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Shipping Code:
RT
C2 Ceramide (3102-57-6) is a cell permeable ceramide analog. Induces apoptosis in a variety of cell types. Stimulates ceramide-activated protein phosphatases. Activates ceramide-activated protein kinases.
References/Citations:
1) Minano et al. (2008), C2-ceramide mediates cerebellar granule cells apoptosis by activation of caspases-2, -9, and -3; J. Neurosci. Res., 86 1734
2) Prinetti et al. (1997), Involvement of a ceramide activated protein phosphatase in the differentiation of neuroblastoma Neuro2a cells; FEBS Lett., 414 475
3) Zhang et al. (1997), Kinase suppressor of Ras is ceramide-activated protein kinase; Cell, 89 63
4) Matsuzaka et al. (2016) Characterization and Functional Analysis of Extracellular Vesicles and Muscle-Abundant miRNAs (miR-1, miR-133a, and miR-206) in C2C12 Myocytes and mdx Mice; PLoS One 11(12) e0167811 [Focus Biomolecules Citation]
5) Matsuzaka et al. (2016) Characterization and functional analysis of extracellular vesicles and muscle-abundant miRNA in C2C12 myocytes and Mdx mice; PLoS One 11(12) e0167811 [Focus Biomolecules Citation]
CAS:
3102-57-6
Catalog Number:
10-1181
Activity:
Cell permeable ceramide
Chemical Name:
N-Acetyl-D-erythro-sphingosine
Molecular Weight:
341.54
Molecular Formula:
C20H39NO3
Solubility:
Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 25 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Shipping Code:
RT
Safety Data Sheet:
N/A
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a restocking/refund fee
C2 Ceramide (3102-57-6) is a cell permeable ceramide analog. Induces apoptosis in a variety of cell types. Stimulates ceramide-activated protein phosphatases. Activates ceramide-activated protein kinases.
References/Citations:
1) Minano et al. (2008), C2-ceramide mediates cerebellar granule cells apoptosis by activation of caspases-2, -9, and -3; J. Neurosci. Res., 86 1734
2) Prinetti et al. (1997), Involvement of a ceramide activated protein phosphatase in the differentiation of neuroblastoma Neuro2a cells; FEBS Lett., 414 475
3) Zhang et al. (1997), Kinase suppressor of Ras is ceramide-activated protein kinase; Cell, 89 63
4) Matsuzaka et al. (2016) Characterization and Functional Analysis of Extracellular Vesicles and Muscle-Abundant miRNAs (miR-1, miR-133a, and miR-206) in C2C12 Myocytes and mdx Mice; PLoS One 11(12) e0167811 [Focus Biomolecules Citation]
5) Matsuzaka et al. (2016) Characterization and functional analysis of extracellular vesicles and muscle-abundant miRNA in C2C12 myocytes and Mdx mice; PLoS One 11(12) e0167811 [Focus Biomolecules Citation]
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