CD4 Antibody
Referência OACD02328-100UL
Tamanho : 100ul
Marca : Aviva Systems Biology
Contactar o distribuidor local :
Telefone : +1 850 650 7790
| Datasheets/Manuals | Printable datasheet for CD4 Antibody (OACD02328) |
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| Predicted Species Reactivity | Human|Mouse|Simian |
|---|---|
| Product Format | Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Application | ICC, IHC, IP, WB |
| Reconstitution and Storage | 2°C to 8°C|-20°C |
| Immunogen | Range: Lys26 - Pro396 |
| Purification | Affinity Purified; Protein A Purified |
| Concentration | 0.5 mg/ml |
| Preservative | 0.02% NaN3 |
| Specificity | The antibody is a rabbit polyclonal antibody raised against CD4. It has been selected for its ability to recognize CD4 in immunohistochemical staining and western blotting. |
| Formulation | PBS, pH7.4, containing 0.02% NaN3, 50% glycerol |
| Application Data | Western blotting: 1:50-400 Immunocytochemistry in formalin fixed cells: 1:50-500 Immunohistochemistry in formalin fixed frozen section: 1:50-500 Immunohistochemistry in paraffin section: 1:10-100 Enzyme-linked Immunosorbent Assay: 1:100-1:5,000 Optimal working dilutions must be determined by end user. |
| Gene Symbol | CD4 |
|---|---|
| Gene Full Name | CD4 molecule |
| Alias Symbols | CD4 antigen;T-cell surface antigen T4/Leu-3;T-cell surface glycoprotein CD4. |
| NCBI Gene Id | 713807 |
| Protein Name | T-cell surface glycoprotein CD4 |
| Description of Target | Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells. In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK-independent pathway. Participates in the development of T-helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages. |
| Uniprot ID | P16003 |
| Protein Accession # | NP_001036127.1 |
| Nucleotide Accession # | NM_001042662 |
| Molecular Weight | 51 kDa |
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What is the species homology for "CD4 Antibody (OACD02328)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Simian".
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How long will it take to receive "CD4 Antibody (OACD02328)"?
This item is available "Domestic: within 1-2 weeks delivery | International: within 1-2 weeks delivery".
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What buffer format is "CD4 Antibody (OACD02328)" provided in?
This item is provided in "Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "CD4 Antibody (OACD02328)"?
This target may also be called "CD4 antigen;T-cell surface antigen T4/Leu-3;T-cell surface glycoprotein CD4." in publications.
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What is the shipping cost for "CD4 Antibody (OACD02328)"?
The shipping cost for this item is within the US. Please contact us for specific shipping for international orders.
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What is the guarantee for "CD4 Antibody (OACD02328)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "CD4 Antibody (OACD02328)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "51 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "CD4 Antibody (OACD02328)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "CD4"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "CD4"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "CD4"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "CD4"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "CD4"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "CD4"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.