Chamaechromone [93413-00-4]
Referência HY-133721-10mg
Tamanho : 10mg
Marca : MedChemExpress
Chamaechromone is a biflavonoid ingredient isolated from the roots of Stellera chamaejasme L. (Thymelaeaceae). Chamaechromone possesses anti-hepatitis B virus (HBV) effects against the surface antigen of HBV (HBsAg) secretion and has insecticidal activities.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
Chamaechromone Chemical Structure
CAS No. : 93413-00-4
This product is a controlled substance and not for sale in your territory.
Based on 1 publication(s) in Google Scholar
Description |
Chamaechromone is a biflavonoid ingredient isolated from the roots of Stellera chamaejasme L. (Thymelaeaceae). Chamaechromone possesses anti-hepatitis B virus (HBV) effects against the surface antigen of HBV (HBsAg) secretion and has insecticidal activities[1]. |
||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Masse moléculaire |
542.49 |
||||||||||||
Formule |
C30H22O10 |
||||||||||||
CAS No. |
93413-00-4 |
||||||||||||
Appearance |
Solid |
||||||||||||
Color |
Off-white to light yellow |
||||||||||||
SMILES |
OC(C=C1)=CC=C1C(C2=CC=C(C=C2)O)C(C3=COC4=CC(O)=CC(O)=C4C3=O)C(C5=C(C=C(C=C5O)O)O)=O |
||||||||||||
Structure Classification |
|
||||||||||||
Initial Source |
|
||||||||||||
Livraison | Room temperature in continental US; may vary elsewhere. |
||||||||||||
Stockage |
4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
||||||||||||
Solvant et solubilité |
In Vitro:
DMSO : 100 mg/mL (184.34 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) Preparing
Stock Solutions
View the Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO
+
%
+
%
Tween-80
+
%
Saline
The co-solvents required include: DMSO,
. All of co-solvents are available by MedChemExpress (MCE).
, Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Calculation results:
Working solution concentration:
mg/mL
Method for preparing stock solution:
mg
drug dissolved in
μL
DMSO (Stock solution concentration: mg/mL).
*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
Method for preparing in vivo working solution for animal experiments: Take
μL DMSO stock solution, add
μL .
μL , mix evenly, next add
μL Tween 80, mix evenly, then add
μL Saline.
If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
|
||||||||||||
Pureté et documentation |
Purity: 99.81% |
||||||||||||
Références |
|
Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
---|
DMSO | 1 mM | 1.8434 mL | 9.2168 mL | 18.4335 mL | 46.0838 mL |
5 mM | 0.3687 mL | 1.8434 mL | 3.6867 mL | 9.2168 mL | |
10 mM | 0.1843 mL | 0.9217 mL | 1.8434 mL | 4.6084 mL | |
15 mM | 0.1229 mL | 0.6145 mL | 1.2289 mL | 3.0723 mL | |
20 mM | 0.0922 mL | 0.4608 mL | 0.9217 mL | 2.3042 mL | |
25 mM | 0.0737 mL | 0.3687 mL | 0.7373 mL | 1.8434 mL | |
30 mM | 0.0614 mL | 0.3072 mL | 0.6145 mL | 1.5361 mL | |
40 mM | 0.0461 mL | 0.2304 mL | 0.4608 mL | 1.1521 mL | |
50 mM | 0.0369 mL | 0.1843 mL | 0.3687 mL | 0.9217 mL | |
60 mM | 0.0307 mL | 0.1536 mL | 0.3072 mL | 0.7681 mL | |
80 mM | 0.0230 mL | 0.1152 mL | 0.2304 mL | 0.5760 mL | |
100 mM | 0.0184 mL | 0.0922 mL | 0.1843 mL | 0.4608 mL |
Chamaechromone Related Classifications
- Inflammation/Immunology Infection
- Anti-infection
- HBV