Dopamine D3 receptor ligand-2 [2882828-95-5]

Dopamine D3 receptor ligand-2 (compound 8) is a potent D₃ receptor ligand with a K_i of 11.4 nM. Dopamine D3 receptor ligand-2 have high selectivity for D₃ over D₂ (K_i=1228 nM)^[1].

439.55

C₂₇H₂₉N₅O

2882828-95-5

N#CC1=CC(N2CCN(CC2)CCCCC(NC3=CC=C(C=C3)C4=NC=CC=C4)=O)=CC=C1

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Benjamin E. Blass, et al. Synthesis of functionalized 5-(4-arylpiperazin-1-yl)-N-arylpentanamides and their evaluation as D3 receptor ligands. Medicinal Chemistry Research volume 31, pages735–748 (2022).