Dopamine D3 receptor ligand-4 [2376333-77-4]

Dopamine D3 receptor ligand-4 (compound 6) is a potent and selective dopamine D₃ receptor ligand, with a K_i of 0.5 nM. Dopamine D3 receptor ligand-4 shows high level of selectivity for D₃ over D₂ (K_i=7.43 nM)^[1].

444.59

C₂₆H₂₈N₄OS

2376333-77-4

O=C(NCCCCN1CCN(C2=CC=CC(C#N)=C2)CC1)C3=CC=C(C4=CSC=C4)C=C3

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Blass BE, et al. Design, synthesis, and evaluation of functionalized 5-(4-arylpiperazin-1-yl)-N-arylpentanamides as selective dopamine D3 receptor ligands. Med Chem Res 31, 132-145 (2022).