Epidermal Growth Factor; human EGF

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Tamanho : 100ug

Telefone : +1 850 650 7790

Telefone : +1 850 650 7790

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: Product Description: EGF, Epidermal Growth Factor, human: EGF was originally discovered in crude preparations of nerve growth factor prepared from mouse submaxillary glands as an activity that induced early eyelid opening, incisor eruption, hair growth inhibition, and stunting of growth when injected into newborn mice. Human EGF was isolated from urine based on its inhibitory effect on gastric secretion and named urogastrone, accordingly. EGF is prototypic of a family of growth factors that are derived from membrane-anchored precursors. All members of this family are characterized by the presence of at least one EGF structural unit (defined by the presence of a conserved 6 cysteine motif that forms three disulfide bonds) in their extracellular domain. EGF is initially synthesized as a 130 kDa precursor transmembrane protein containing 9 EGF units. The mature soluble EGF sequence corresponds to the EGF unit located proximal to the transmembrane domain. The membrane EGF precursor is capable of binding to the EGF receptor and was reported to be biologically active., UnitProt ID: P01133

Total Product Size:
RC216-15 (100ug)
RC216-15 (500ug)
RC216-15 (1mg)

Number of Containers: 1

Refrigeration Requirements: Freezer

Shipping Conditions: ICE

UNSPSC Code: 12352202

UNSPSC Category: Other Growth Factors
Documents: Product Info. (152.01 KB)

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