Interleukin-8 (IL-8), also known as CXCL8, is a CXC family member chemokine produced by macrophages and other cell types such as epithelial cells. There have been 17 different CXC chemokines described in mammals, that are subdivided into two categories, those with a specific amino acid sequence (or motif) of glutamic acid-leucine-arginine (or ELR for short) immediately before the first cysteine of the CXC motif (ELR-positive), and those without an ELR motif (ELR-negative). ELR-positive CXC chemokines such as IL-8 specifically induce the migration of neutrophils, and interact with chemokine receptors CXCR1 and CXCR2.

Reactivity - ELISA
Bovine IL-8 - None
Canine IL-8 - None
Dolphin IL-8 - None
Equine IL-8 - Strong
Feline IL-8 - Weak
Guinea Pig IL-8 - None
Human IL-8 - None
 

Equine IL-8 ELISA Data