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> GZMA Recombinant Protein

GZMA Recombinant Protein

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Referência OPCD08056-10UG

Tamanho : 10ug

Marca : Aviva Systems Biology

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Datasheets/ManualsPrintable datasheet for GZMA Recombinant Protein (OPCD08056)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 5% Trehalose.
HostYeast
ConjugationUnconjugated
ApplicationCtrl (+), SDS-PAGE, WB
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Ile29-Val262
::Subcellular Location: Secreted
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
SourceYeast
TagN-terminal His Tag
Gene SymbolGZMA
Gene Full Namegranzyme A
Alias SymbolsCTL tryptase;CTLA3;cytotoxic T-lymphocyte proteinase 1;Cytotoxic T-lymphocyte-associated serine esterase-3;fragmentin-1;granzyme 1;granzyme A;Granzyme A (Cytotoxic T-lymphocyte-associated serine esterase-3; Hanukah factor serine protease);granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3);Granzyme-1;h factor;Hanukah factor serine protease);Hanukkah factor;HF;HFSP.
NCBI Gene Id3001
Protein NameGranzyme A
Description of TargetAbundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA.
Uniprot IDP12544
Protein Accession #NP_006135.1
Nucleotide Accession #NM_006144.3
Protein Size (# AA)Ile29~Val262
Molecular Weight28kDa