Human Calcium independent Phospholipase A2 (PLA2G6) activation kit by CRISPRa

Referência GA105547

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Human Calcium independent Phospholipase A2 (PLA2G6) activation kit by CRISPRa

Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PLA2G6
Locus ID 8398
Components

GA105547G1, Calcium independent Phospholipase A2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105547G2, Calcium independent Phospholipase A2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105547G3, Calcium independent Phospholipase A2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001004426, NM_001199562, NM_003560, NM_001349864, NM_001349865, NM_001349866, NM_001349867, NM_001349868, NM_001349869
UniProt ID O60733
Synonyms CaI-PLA2; GVI; INAD1; iPLA2; IPLA2-VIA; iPLA2beta; NBIA2; NBIA2A; NBIA2B; PARK14; PLA2; PNPLA9
Summary The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date. [provided by RefSeq, Dec 2010]
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SKU Description Size
KN207546 PLA2G6 - human gene knockout kit via CRISPR, HDR mediated 1 kit
KN207546BN PLA2G6 - human gene knockout kit via CRISPR, HDR mediated 1 kit
KN207546LP PLA2G6 - human gene knockout kit via CRISPR, HDR mediated 1 kit
KN207546RB PLA2G6 - human gene knockout kit via CRISPR, HDR mediated 1 kit
KN407546 PLA2G6 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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