Human Cancer Antigen CA 15-3 ELISA kit

Referência EA100979

Tamanho : 1x96wells

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Human Cancer Antigen CA 15-3 ELISA kit

Specifications
Product Data
ACCN NM_002456
Assay Length 4 hours
Assay Platform 96-well plate
Assay Type Solid Phase Sandwich ELISA
Assay Type Sandwich
Background This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011]
Cross Reactivity N/A
Curve Range Standard Curve Range: 0-240 U/ml
figure_legend Representative standard curve for CA15-3 ELISA
Format 96-well strip plate
Gene Symbol MUC1
Interference No significant interference observed with available related molecules.
Locus ID 4582
Reactivity Human
Reactivity Human
Reactivity Human
Sample Type Human serum
Sample Volume 20 ul
Sensitivity Minimum Sensitivity: 5.0 U/ml
Signal Colorimetric
Species Human
Specificity This kit is used for quantitative detection of human CA15-3
Standard Curve /assets/images/elisa/kits/132/bc-1015-1-e.jpg
Target Symbol MUC1
Description Human Cancer Antigen CA 15-3 ELISA kit
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