Human HDAC4 activation kit by CRISPRa
Referência GA106565
Tamanho : 1kit
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Human HDAC4 activation kit by CRISPRa
SKU
GA106565
HDAC4 CRISPRa kit - CRISPR gene activation of human histone deacetylase 4
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | HDAC4 |
| Locus ID | 9759 |
| Components | GA106565G1, HDAC4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106565G2, HDAC4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106565G3, HDAC4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_006037 |
| UniProt ID | P56524 |
| Synonyms | AHO3; BDMR; HA6116; HD4; HDAC-4; HDAC-A; HDACA |
| Summary | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN411495 | HDAC4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.