Human Insulin ELISA kit
Referência EA100870
Tamanho : 1x96wells
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Human Insulin ELISA kit
| Product Data | |
| Species | Human |
|---|---|
| Format | 8x12 divisible strips |
| Assay Type | Solid Phase Sandwich ELISA |
| Assay Length | 3 hours |
| Signal | Colorimetric |
| Curve Range | 2.6 -66 pmol/l |
| Sample Type | Serum |
| Sample Volume | 25 pmol/l |
| Reactivity | Human |
| Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
| Interference | No significant interference observed with available related molecules. |
| Components |
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| Background | Insulin is the principal hormone responsible for the control of glucose metabolism. It is synthesized in the β- cells of the islets of Langerhans as the precursor, proinsulin, which is processed to form C-peptide and insulin. Both are secreted in equimolar amounts into the portal circulation. The mature insulin molecule comprises two polypeptide chains, the A chain and B chain (21 and 30 amino acids respectively). The two chains are linked together by two inter-chain disulphide bridges. There is also an intra-chain disulphide bridge in the A chain. Insulin concentrations are severely reduced in insulin-dependent diabetes mellitus (IDDM) and some other conditions such as hypopituitarism. Insulin levels are raised in non-insulin- dependent diabetes mellitus (NIDDM), obesity, insulinoma and some endocrine dysfunctions such as Cushing" data-toggle="trigger" href="#reviews" id="tab-label-reviews-title"> Reviews Write Your Own Review Citations |