Human Methylmalonyl Coenzyme A mutase (MUT) activation kit by CRISPRa

Referência GA103041

Tamanho : 1kit

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Human Methylmalonyl Coenzyme A mutase (MUT) activation kit by CRISPRa

Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MMUT
Locus ID 4594
Components

GA103041G1, Methylmalonyl Coenzyme A mutase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103041G2, Methylmalonyl Coenzyme A mutase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103041G3, Methylmalonyl Coenzyme A mutase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_000255
UniProt ID P22033
Synonyms MCM
Summary This gene encodes the mitochondrial enzyme methylmalonyl Coenzyme A mutase. In humans, the product of this gene is a vitamin B12-dependent enzyme which catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA, while in other species this enzyme may have different functions. Mutations in this gene may lead to various types of methylmalonic aciduria. [provided by RefSeq, Jul 2008]
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SKU Description Size
KN401972 MUT - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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