Human Phospholipase A2 (PLB1) activation kit by CRISPRa
Referência GA115776
Tamanho : 1kit
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Human Phospholipase A2 (PLB1) activation kit by CRISPRa
SKU
GA115776
PLB1 CRISPRa kit - CRISPR gene activation of human phospholipase B1
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | PLB1 |
| Locus ID | 151056 |
| Components | GA115776G1, Phospholipase A2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115776G2, Phospholipase A2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115776G3, Phospholipase A2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_001170585, NM_153021, NR_138141 |
| UniProt ID | Q6P1J6 |
| Synonyms | PLB; PLB/LIP |
| Summary | This gene encodes a membrane-associated phospholipase that displays lysophospholipase and phospholipase A2 activities through removal of sn-1 and sn-2 fatty acids of glycerophospholipids. In addition, it displays lipase and retinyl ester hydrolase activities. The encoded protein is highly conserved and is composed of a large, glycosylated extracellular domain composed of four tandem homologous domains, followed by a hydrophobic segment that anchors the enzyme to the membrane and a short C-terminal cytoplasmic tail. This gene has been identified as a candidate rheumatoid arthritis risk gene. [provided by RefSeq, Jul 2016] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN418730 | PLB1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.