Human sphingosine 1 phosphate phosphatase 1 (SGPP1) activation kit by CRISPRa
Referência GA113051
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Human sphingosine 1 phosphate phosphatase 1 (SGPP1) activation kit by CRISPRa
SKU
GA113051
SGPP1 CRISPRa kit - CRISPR gene activation of human sphingosine-1-phosphate phosphatase 1
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | SGPP1 |
| Locus ID | 81537 |
| Components | GA113051G1, sphingosine 1 phosphate phosphatase 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113051G2, sphingosine 1 phosphate phosphatase 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113051G3, sphingosine 1 phosphate phosphatase 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_030791 |
| UniProt ID | Q9BX95 |
| Synonyms | SPPase1 |
| Summary | Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes. SGPP1 catalyzes the degradation of S1P via salvage and recycling of sphingosine into long-chain ceramides (Mandala et al., 2000 [PubMed 10859351]; Le Stunff et al., 2007 [PubMed 17895250]).[supplied by OMIM, Jun 2009] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN409497 | SGPP1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.