IOX1

P022-5MG IOX1, 5 mg In Stock
P022-25MG IOX1, 25 mg In Stock
  • Features Inhibitor of Jumonji HDMs
  • Broad spectrum 2-oxoglutarate oxygenase inhibitor
  • Cell Permeable

Inhibits the JMJD family of 2-oxoglutarate-dependent histone demethylases. IC50 = 0.12, 0.07, 0.2, 0.3, 0.6, and 1 μM for JMJD3, JMJD1A, JMJD2A, JMJD2E, JMJD2C and UTX respectively. Is a broad spectrum 2-oxoglutarate oxygenase inhibitor which may be used to study hypoxic signaling. Cell permeable.