Mouse Anti-Human CD45RA-PE
Referência 9630-09
Tamanho : 100tests
Marca : Southern Biotech
Contactar o distribuidor local :
Telefone : +1 850 650 7790
| Clone | F8-11-13 |
|---|---|
| Isotype | Mouse (BALB/c) IgG1κ |
| Isotype Control | Mouse IgG1-PE (15H6) |
| Specificity | Human CD45RA |
| Description | CD45RA is a 220 kDa exon A-dependent isoform of CD45. It is expressed on 40-50% of CD4+ peripheral T cells, 50% of peripheral CD8+ T cells, and a portion of B lymphocytes and monocytes. |
| Immunogen | Purified lymphocytes from human lymph nodes |
| Conjugate | PE (R-phycoerythrin) |
| Buffer Formulation | Phosphate buffered saline containing < 0.1% sodium azide and a stabilizer |
| Clonality | Monoclonal |
| Concentration | Lot specific |
| Volume | 1.0 mL |
| Recommended Storage | 2-8°C; Avoid exposure to light; Do not freeze |
| Applications | Flow Cytometry – Quality tested 1,5-7 Immunohistochemistry-Frozen Sections – Reported in literature 2,3 Immunohistochemistry-Paraffin Sections – Reported in literature 2,3 Immunoprecipitation – Reported in literature 4 Purification – Reported in literature 1 |
| RRID Number | AB_2797037 |
| Gene ID | 5788 (Human) |
| Gene ID Symbol | PTPRC (Human) |
| Gene ID Aliases | B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200 |
| UniProt ID | P08575 (Human |
| UniProt Name | PTPRC_HUMAN (Human) |
Documentation
Technical Bulletin Safety Datasheet
Certificate of Analysis Lookup
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- 1. Dalchau R, Fabre JW. Identification with a monoclonal antibody of a predominantly B lymphocyte-specific determinant of the human leukocyte common antigen. Evidence for structural and possible functional diversity of the human leukocyte common molecule. J Exp Med. 1981;153:753-65. (Immunogen, FC)
- 2. Salter DM, Krajewski AS, Dewar AE. Immunophenotype analysis of malignant histiocytosis of the intestine. J Clin Pathol. 1986;39:8-15. (IHC-FS, IHC-PS)
- 3. Berti E, Tomasini D, Vermeer MH, Meijer CJ, Alessi E, Willemze R. Primary cutaneous CD8-positive epidermotropic cytotoxic T cell lymphomas. A distinct clinicopathological entity with an aggressive clinical behavior. Am J Pathol. 1999;155:483-92. (IHC-PS, IHC-FS)
- 4. Cappione AJ, Pugh-Bernard AE, Anolik JH, Sanz I. Lupus IgG VH4.34 antibodies bind to a 220-kDa glycoform of CD45/B220 on the surface of human B lymphocytes. J Immunol. 2004;172:4298-307. (IP)
- 5. Lantelme E, Mantovani S, Palermo B, Campanelli R, Sallusto F, Giachino C. Kinetics of GATA-3 gene expression in early polarizing and committed human T cells. Immunology. 2001;102:123-30. (FC)
- 6. Porras F, Urrea F, Ortiz B, Martínez-Cairo S, Bouquelet S, Martínez G, et al. Isolation of the receptor for the Amaranthus leucocarpus lectin from human T lymphocytes. Biochim Biophys Acta. 2005;1724:155-62. (FC)
- 7. Jiménez-Martínez MC, Lascurain R, Méndez-Reguera A, Estrada-Parra S, Estrada-García I, Gorocica P, et al. O-glycosylation of NnTreg lymphocytes recognized by the Amaranthus leucocarpus lectin. Clin Dev Immunol. 2013;2013:506807. (FC)