Mouse Anti-PHOX2B Monoclonal Anibody (Clone : 2B0)

Referência FNab06409

Tamanho : 100ug

Marca : FineTest

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Synonyms:Paired mesoderm homeobox protein 2B|Neuroblastoma Phox (NBPhox)|PHOX2B homeodomain protein|Paired-like homeobox 2B|PHOX2B|PMX2B antibody
Catalogue No.:FNab06409Reactivity:Human, Mouse
Host:MouseTested Application:ELISA, IHC, WB
Clonality:monoclonalIsotype:IgG1
Size
100µg Inquiry
Dispatch Time: About 3 working days
Product Name
PHOX2B antibody
Catalogue No.
FNab06409
Size
100μg
Form
liquid
Purification
Protein A+G purification
Purity
≥95% as determined by SDS-PAGE
Clonality
monoclonal
Isotype
IgG1
Clone ID
2B0
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
paired-like homeobox 2b
Alternative Names
Paired mesoderm homeobox protein 2B|Neuroblastoma Phox (NBPhox)|PHOX2B homeodomain protein|Paired-like homeobox 2B|PHOX2B|PMX2B antibody
UniProt ID
Q99453
Observed MW
35 kDa
Application
Tested Applications
ELISA, IHC, WB
Recommended dilution
WB: 1:1000-1:5000; IHC: 1:20-1:200
Validated Images
Neuro-2a cells were subjected to SDS PAGE followed by western blot with FNab06409(PHOX2B Antibody) at dilution of 1:2500
Immunohistochemistry of paraffin-embedded neuroblastoma tissue slide using FNab06409(PHOX2B Antibody) at dilution of 1:50
Background
Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element.
Journal:
bioRxiv
Author:
Cellular Senescence, Cancer & Aging team, Equipe Labellisée la Ligue Contre le Cancer, Cancer Research Center of Lyon, INSERM U1052, CNRS UMR 5286, Centre Léon Bérard, Lyon University, Consortium South-ROCK, Institut Convergence Plascan, Lyon, France;
Sample:
neuroblastoma fresh tissue
Cited Date:
2024-09-06
Product:

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9200-01
 0.5mg