Mouse Hdac8 activation kit by CRISPRa
Referência GA208474
Tamanho : 1kit
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Mouse Hdac8 activation kit by CRISPRa
SKU
GA208474
Hdac8 CRISPRa kit - CRISPR gene activation of mouse histone deacetylase 8
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | Hdac8 |
| Locus ID | 70315 |
| Components | GA208474G1, Hdac8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208474G2, Hdac8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208474G3, Hdac8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_001313742, NM_027382 |
| UniProt ID | Q8VH37 |
| Synonyms | 2610007D20Rik |
| Summary | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility (By similarity).[UniProtKB/Swiss-Prot Function] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN507623 | Hdac8 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.