Mouse Mmp9 activation kit by CRISPRa
Referência GA202686
Tamanho : 1kit
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Mouse Mmp9 activation kit by CRISPRa
SKU
GA202686
Mmp9 CRISPRa kit - CRISPR gene activation of mouse matrix metallopeptidase 9
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | Mmp9 |
| Locus ID | 17395 |
| Components | GA202686G1, Mmp9 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202686G2, Mmp9 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202686G3, Mmp9 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_013599 |
| UniProt ID | P41245 |
| Synonyms | AW743869; B/MMP9; Clg4b; Gel B; MMP-9; pro-MMP-9 |
| Summary | This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprotein undergoes proteolytic processing to generate a mature, zinc-dependent endopeptidase enzyme that degrades collagens of type IV, V and XI, and elastin. Mice lacking the encoded protein exhibit an abnormal pattern of skeletal growth plate vascularization and ossification, reduced keratinocyte hyperproliferation at all neoplastic stages, a decreased incidence of invasive tumors, and resistance to experimental autoimmune encephalomyelitis. [provided by RefSeq, Feb 2016] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN510185 | Mmp9 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.