Powder: -20°C for 3 years | In solvent: -80°C for 1 year
N-Nitroso Sarcosine [13256-22-9]
Referência T36414-500mg
Tamanho : 500mg
Marca : TargetMol
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N-Nitroso Sarcosine
Catalog No. T36414 CAS 13256-22-9
N-Nitroso sarcosine is a carcinogen and nitrosation product of sarcosine that has been found in cured meat products.1,2
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N-Nitroso Sarcosine, CAS 13256-22-9
| Pack Size | /USD | |
|---|---|---|
| 10 mg | 35 days | |
| 100 mg | 35 days |
Contact us for more batch information
| Description | N-Nitroso sarcosine is a carcinogen and nitrosation product of sarcosine that has been found in cured meat products.1,2 |
| In vivo | In vivo, N-nitroso sarcosine (225 mg/kg) induces the formation of metastatic liver carcinomas in mice.2 |
| Molecular Weight | 118.0913 |
| Formula | C3H6N2O3 |
| CAS No. | 13256-22-9 |
Storage
Solubility Information
DMSO: 10 mg/mL
DMF: 15 mg/mL
Ethanol: 30 mg/mL
PBS (pH 7.2): 5 mg/mL
References and Literature
1. Janzowski, C., Eisenbrand, G., and Preussmann, R.Occurrence of N-nitrosamino acids in cured meat products and their efffect on formation of N-nitrosamines during heatingFood Cosmet. Toxicol.16(4)343-348(1978) 2. Wogan, G.N., Paglialunga, S., Archer, M.C., et al.Carcinogenicity of nitrosation products of ephedrine, sarcosine, folic acid, and creatinineCancer Res.35(8)1981-1984(1975)
Dose Conversion
You can also refer to dose conversion for different animals. More
In vivo Formulation Calculator (Clear solution)
Step One: Enter information below
Dosage
mg/kg Average weight of animals
g Dosing volume per animal
ul Number of animals
Step Two: Enter the in vivo formulation
% DMSO
%
% Tween 80
% ddH2O
%DMSO
%
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，
Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH2O, mix and clarify.
Note:
Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Keywords
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