SP3176a | Platelet Membrane Glycoprotein IIB Peptide (296-306) Quimigen

Product Information
Primary Accession	Q9QUM0
Other Accession	P08514
Sequence	NH2-TDVNGDGRHDL-COOH

Additional Information
Gene ID	16399
Other Names	Integrin alpha-IIb, GPalpha IIb, GPIIb, Platelet membrane glycoprotein IIb, CD41, Integrin alpha-IIb heavy chain, Integrin alpha-IIb light chain, Itga2b
Format	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Storage	Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Precautions	This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Protein Information
Name	Itga2b
Function	Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
Cellular Location	Membrane; Single-pass type I membrane protein.

Research Areas

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