Prazosin
Referência M5894-5mg
Tamanho : 5mg
Marca : AbMole Bioscience
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All AbMole products are for research use only, cannot be used for human consumption.
Quality Control & Documentation
Biological Activity
Prazosin is a well-tolerated, CNS-active α1-adrenergic receptor antagonist for the research of high blood pressure and alcohol use disorders. Prazosin potently inhibits Norepinephrine (NE)-stimulated 45Ca efflux with an IC50 of 0.15 nM. Prazosin inhibits organic cation transporters OCT-1 and OCT-3 with IC50s of 1.8, and 13 μM, respectively.
Chemical Information
| Molecular Weight | 383.4 |
| Formula | C19H21N5O4 |
| CAS Number | 19216-56-9 |
| Solubility (25°C) | DMSO 40 mg/mL |
| Storage | Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
References
[1] De Berardis D, et al. Curr Drug Targets. Targeting the Noradrenergic System in Posttraumatic Stress Disorder: A Systematic Review and Meta-Analysis of Prazosin Trials.