PTCH1 (NM_000264) Human 3' UTR Clone
Referência SC220803
Tamanho : 10µg
Contactar o distribuidor local :
PTCH1 (NM_000264) Human 3' UTR Clone
| Product Data | |
| Vector | pMirTarget |
|---|---|
| Species | Human |
| transfection_reporter | RFP |
| assay_reporter | Luciferase |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Target Symbol | PTCH1 |
| Synonyms | BCNS; NBCCS; PTC; PTC1; PTCH |
| ACCN | NM_000264 |
| Insert Size | 2000 bp |
| Sequence Data | Insert Sequence >SC220803 3’UTR clone of NM_000264 The sequence shown below is from the reference sequence of NM_000264. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAGAGGCCCCGGGGAAGCAGCTCCAACTGAGGGTGATTAAAATCTGAAGCAAAGAGGCCAAAGATTGGA AACCCCCCACCCCCACCTCTTTCCAGAACTGCTTGAAGAGAACTGGTTGGAGTTATGGAAAAGATGCCC TGTGCCAGGACAGCAGTTCATTGTTACTGTAACCGATTGTATTATTTTGTTAAATATTTCTATAAATAT TTAAGAGATGTACACATGTGTAATATAGGAAGGAAGGATGTAAAGTGGTATGATCTGGGGCTTCTCCAC TCCTGCCCCAGAGTGTGGAGGCCACAGTGGGGCCTCTCCGTATTTGTGCATTGGGCTCCGTGCCACAAC CAAGCTTCATTAGTCTTAAATTTCAGCATATGTTGCTGCTGCTTAAATATTGTATAATTTACTTGTATA ATTCTATGCAAATATTGCTTATGTAATAGGATTATTTTGTAAAGGTTTCTGTTTAAAATATTTTAAATT TGCATATCACAACCCTGTGGTAGTATGAAATGTTACTGTTAACTTTCAAACACGCTATGCGTGATAATT TTTTTGTTTAATGAGCAGATATGAAGAAAGCACGTTAATCCTGGTGGCTTCTCTAGGTGTCGTTGTGTG CGGTCCTCTTGTTTGGCTGTGCGTGTGAACACGTGTGTGAGTTCACCATGTACTGTACTGTGATTTTTT TTTTGTCTTGTTTTGTTTCTCTACACTGTCTGTAACCTGTAGTAGGCTCTGACCTAGTCAGGCTGGAAG CGTCAGGATATCTTTTCTTCGTGCTGGTGAGGGCTGGCCCTAAACATCCACCTAATCCTTTCAAATCAG CCCGGCAAAAGCTAGACTCTCCTCGTGTCTACGGCATCTCTTATGATCATTGGCTGCCATCCAGGACCC CAATTTGTGCTTCAGGGGGATAATCTCCTTCTCTCGGATCATTGTGATGGATGCTGGAACCTCAGGGTA TGGAGCTCACATCAGTTCATCATGGTGGGTGTTAGAGAATTCGGTGACATGCCTAGTGCTGAGCCTTGG CTGGGCCATGAGAGTCTGTATACTCTAAAAAGCATGCAGCATGGTGCCCCTCTTCTGACCAACACACAC ACGACCCCTCCCCCAACACCCCCAAATTCAAGAGTGGATGTGGCCCTGTCACAGGTAGAAAAACCTATT TAGTTAATTCTTTCTTGGCCCACAGTCTCCCAGAAATGATGTTTTGAGTCCCTATAGTTTAAACTCCCT CTCTTAAATGGAGCAGCTGGTTGAGGCTTTCTAGATCTGTTTGCATCTTCTTTAAAACTAAGTGGTGAG CATGCATTGTGGTGTAGAGGCAGGCATTATGTAGGATAAGAGCTCCGGGGGGATTCTTCATGCACCAGT GTTTAGGGTACGTGCTTCCTAAGTAAATCCAAACATTGTCTCCATCCTCCCCGTCATTAGTGCTCTTTC AATGTGATGTGGGAAAGCAGGAGGATGGACACACCCCACTGAAAGATGTAGGCAGGGGCAGGTCTCTCA ACCAGGCATATTTTTAAAAGTTGCTTCTGTACTGGTTCTCTTCTTTTGCTCTGAGGTGTGGGCTCCCTC ATCTCGTAACCAGAGACCAGCACATGTCAGGGAAGCACCCAGTGTCGGCTCCCCATCCAAATCCACACC AGCACCTTGTTACAGACAAGAAGTCAGAGGAAAGGGCGGGGTCCCTGCAGGGCTGAAGCCTAAGCTACT GTGAGGCGCTCACGAGTGGCAGCTCCTGTTACTCCCTTTTAAATTACCTGGGAAATCTTAACAGAAAGG TAATGGGCCCCCAGAAATACCCACAGCATAGTGACCTCAGACCCTGATACTCACCACAAAACTTTTAAG ATGCTGATTGGGAGCCGCTTGTGGCTGCTGGGTGTGTGTGTGTGTGTGTGCGTGCGTGCGTGTGTGTGT GTCTCTGCTGGGGACCCTGGCCACCCCCCTGCTGCTGTCTTGGTGCCTGTCACCCACATGGTCTGCCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
| Restriction Sites | SgfI-MluI |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
| Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. |
| Reference Data | |
| RefSeq | NM_000264.5 |
| Locus ID | 5727 |
| Summary | This gene encodes a member of the patched family of proteins and a component of the hedgehog signaling pathway. Hedgehog signaling is important in embryonic development and tumorigenesis. The encoded protein is the receptor for the secreted hedgehog ligands, which include sonic hedgehog, indian hedgehog and desert hedgehog. Following binding by one of the hedgehog ligands, the encoded protein is trafficked away from the primary cilium, relieving inhibition of the G-protein-coupled receptor smoothened, which results in activation of downstream signaling. Mutations of this gene have been associated with basal cell nevus syndrome and holoprosencephaly. [provided by RefSeq, Aug 2017] |