Bacteriostatic antibiotic isolated from strains of Streptomyces, active against gram positive and gram negative bacteria and also against intracellular microorganisms like Rickettsia and mycoplasma. Inhibits bacterial protein synthesis by preventing aminoacyl-RNA binding to the A-side of the 30S ribosomal subunit. Sample analysis (1,2). Used for the selection of resistant clones (3,4).

Assay

min. 900 µg/mg

References:

1. Anderson, C.R. et al. (2005) J. Chromatogr. A 1075, 23-32
2. Koesukwiwat, U. et al. (2007) . J. Chromatogr. A 1140, 147-56
3. Guillaume, G. et al. (2000) FEMS Microbiol. Ecology 32, 77-85
4. Call, D.R. et al. (2003) Antimicrob. Agents Chemother. 47, 3290-5
5. Loftin, K.A. et al. (2005) Environm. Toxicol. Chem. 24, 782-8
6. Munshi, T. et al. (2013) PLOS ONE 8(3): e60143

WARNING

Hazard Statements	H315 - H319 - H335 - H361 - H362
Precautions	P201 - P261 - P280
Reaction	P302 +P352 - P304 +P340 - P305 +P351 +P338

Repr. 2, Lact. • EINECS: 200-593-8 • WGK: 1 • HS: 29413000
Storage Temperature: +15 °C to +30 °C