FGG Recombinant Protein

Cat# OPCD08077-10UG

Size : 10ug

Brand : Aviva Systems Biology

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Datasheets/ManualsPrintable datasheet for FGG Recombinant Protein (OPCD08077)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 5% Trehalose.
HostYeast
ConjugationUnconjugated
ApplicationCtrl (+), SDS-PAGE, WB
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Lys166-Asn416
::Subcellular Location: Secreted
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
SourceYeast
TagN-terminal His Tag
Gene SymbolFGG
Gene Full Namefibrinogen gamma chain
Alias Symbolsfibrinogen gamma chain;fibrinogen, gamma polypeptide;testicular tissue protein Li 70.
NCBI Gene Id2266
Protein NameFibrinogen gamma chain
Description of TargetTogether with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
Uniprot IDP02679
Protein Accession #NP_000500.2
Nucleotide Accession #NM_000509.5
Protein Size (# AA)Lys166~Asn416
Molecular Weight30kDa