Size : 1Kit
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HDAC1 Inhibitor Screening Assay Kit is a fluorescence-based method for screening HDAC1 inhibitors.
For research use only (RUO)
Store the kit at -80°C temporarily. For best results, store the components as described in the protocol.
Result Data
HDAC1
DKFZp686H12203, GON-10, HD1, RPD3, RPD3L1
histone deacetylase 1
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq
OTTHUMP00000008745|reduced potassium dependency, yeast homolog-like 1
Qianqian Qiu, Fanglian Chi, Daoguang Zhou, Zhancheng Xie, Yunxiao Liu, Hanyu Wu, Ziyu Yin, Wei Shi, Hai Qian.
Journal of Medicinal Chemistry 2023 Apr; 66(8):5753.
Application：Func, Chemical, Chemical.
