Human Cathepsin D (CTSD) activation kit by CRISPRa
Cat# GA101067
Size : 1kit
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Human Cathepsin D (CTSD) activation kit by CRISPRa
SKU
GA101067
CTSD CRISPRa kit - CRISPR gene activation of human cathepsin D
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | CTSD |
| Locus ID | 1509 |
| Components | GA101067G1, Cathepsin D gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101067G2, Cathepsin D gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101067G3, Cathepsin D gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_001909 |
| UniProt ID | P07339 |
| Synonyms | CLN10; CPSD; HEL-S-130P |
| Summary | This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN400719 | CTSD - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.