LULLABY 3x1mL siRNA TRANSFECTION REAGENT

Cat# LL73000

Size : 3x1mL

Brand : OZ Biosciences

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Phone : +1 850 650 7790

  • Lullaby Transfection Reagent

Lullaby Transfection Reagent

Lullaby is the ideal siRNA transfection reagent for gene silencing. Relying on the TEE-technology, it has been successfully tested on numerous cell lines, reaching up to 90% gene silencing with high reproducibility and a very low toxicity. RNA interference is a powerful technique to shut down genes expression in cells and organisms. This silencing effect constitutes a very helpful tool to study gene’s function and a promising approach for new therapeutic treatments. Short RNA duplexes (siRNA: small interfering RNA, shRNA: small hairpin RNA and dsRNA: double strand RNA) are extremely selective by interacting and inducing the degradation of their specific mRNA targets and thereby inhibit the resulting protein production. Lullaby® siRNA Transfection Reagent introduces the siRNA duplexes in a variety of cells with a very high efficiency leading to exceptional knockdown effects with low doses of siRNA. 

 "We initially collated a transfection reagent library of 26 reagents...By far, our preferred reagent is Lullaby from OZ Biosciences. We have used this reagent in over 20 cell lines and have found it essential in enabling siRNA screens in hard to tranfect cell lines..., with minimal toxicity"

Emma L. Shanks (2014) Strategic siRNA Screening Approaches to Target Cancer at the Cancer Research UK Beaston Institute, Combinatorial Chemistry & High Throughput Screening, 17:328-332

GENE SILENCING BROCHURE

  • Effective with very low doses of siRNA
  • Minimized off-target effects
  • Suitable for siRNA, shRNA, dsRNA, etc.
  • Applicable to a broad range of cells
  • Serum compatible & Non toxic
  • Straightforward protocol

 

Sizes:

  • 500 µL: Up to 1000 assays
  • 1000 µL: Up to 2000 assays
  • 3 x 1000 µL: Up to 6000 assays

Storage: + 4°C

Shipping conditions: Room temperature

 

 

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A549 siRNA Lullaby Transfection Reagent Jenks AD. bioRxiv 2017. doi https://doi.org/10.1101/180257 A549 siRNA Lullaby Transfection Reagent Zhang Y. Cancer Cell Int. 2016 Dec 1;16:89. A549 siRNA Lullaby Transfection Reagent Kwok T. Arch Virol. 2009;154(1):109-14. A673 siRNA lullaby Transfection Reagent Le AH. J Cell Biol. 2021 Sep 6;220(9):e202012114. AU-565 siRNA Lullaby Transfection Reagent Baenke F. J Pathol. 2015 May 12. doi: 10.1002/path.4562. B16-F1 siRNA Lullaby Transfection Reagent Buracco S. Curr Biol. 2024 https://doi.org/10.1016/j.cub.2024.08.013 B16-F10 siRNA Lullaby Transfection Reagent Whitelax JA. bioRxiv 2024 doi.org/10.1101/2024.03.26.586838 B16-F10 ODN Lullaby Transfection Reagent Noreen F. Oligonucleotides. 2009 Jun;19(2):169-78. Beas-2B siRNA Lullaby Transfection Reagent Lear TB. J Biol Chem 2023 Oct 25:105388. doi: 10.1016/j.jbc.2023.105388. Beas-2B siRNA Lullaby Transfection Reagent Chen Y. Nat Commun. 2021 Jun 23;12(1):3907. 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