CD235a Biotin
Catalog #
Size
RBC gated human blood stained with CD235a Biotin followed by SA-PE (RED); RBC gated human blood stained with mouse IgG1 Biotin followed by SA-PE (BLUE).
| Conjugation | Biotin |
|---|---|
| Antigen | CD235a |
| Clone | GYPA280 |
| Isotype | IgG1, k |
| Applications | FC |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Primary/Secondary | Primary |
| Storage | 2-8°C |
| Status | RUO |
Description:
The clone GYPA280, a mouse monoclonal antibody selectively recognizes 39kd sialoglycoprotein identified as glycophorin A also known as CD235a. CD235a is abundantly expressed on red blood cells and erythroid precursor cells. It has been shown that glycophorin acts on the erythrocyte binding antigen (EBA-175) of P. falciparum as well as the receptor for Sandei virus, parvovirus, influenza virus and hepatitis A virus. Two types of glycophorins are identified and classified as glycophorin A (GPA) and glycophorin B (GPB). Both are trans-membrane sialoglycoproteins. GPA is the career of M and N antigens specific blood group whereas GPB is for the S and U specificities.
The clone GYPA280, a mouse monoclonal antibody selectively recognizes 39kd sialoglycoprotein identified as glycophorin A also known as CD235a. CD235a is abundantly expressed on red blood cells and erythroid precursor cells. It has been shown that glycophorin acts on the erythrocyte binding antigen (EBA-175) of P. falciparum as well as the receptor for Sandei virus, parvovirus, influenza virus and hepatitis A virus. Two types of glycophorins are identified and classified as glycophorin A (GPA) and glycophorin B (GPB). Both are trans-membrane sialoglycoproteins. GPA is the career of M and N antigens specific blood group whereas GPB is for the S and U specificities.