Nilotinib (monohydrochloride monohydrate) [923288-90-8]
Cat# HY-10159A-100mg
Size : 100mg
Brand : MedChemExpress
Description | IC50 & Target |
Bcr-Abl[1] |
---|---|
In Vitro |
Nilotinib (AMN107) monohydrochloride monohydrate, selective Abl inhibitor, is designed to interact with the ATP-binding site of BCR-ABL with a higher affinity than imatinib while being significantly more potent compared with imatinib (IC50<30 nM), also maintains activity against most of the BCR-ABL point mutants that confer Imatinib resistance[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |