IgM Isotype Control

IgM Isotype Control

IgM Isotype Controls are antibodies that match the IgM class and subclass of the primary antibody used in an experiment but lack specificity for any target antigen present in the sample. This means they do not bind to any specific proteins in the cells or tissues being analyzed. The primary function of using an IgM isotype control is to help researchers identify and quantify non-specific binding that may interfere with the interpretation of experimental results.

Importance of IgM isotype controls

IgM isotype controls are crucial for:

  • Differentiation of Specific and Non-Specific Binding: IgM isotype controls are essential for distinguishing between specific signals generated by target antibodies and non-specific background signals. Non-specific binding can occur due to:
    • Fc receptor interactions: IgM antibodies can bind to Fc receptors on various immune cells, leading to potential confounding signals.
    • Non-specific interactions: These can arise from binding to cellular proteins or other components within the sample.
    • Cellular autofluorescence: This phenomenon can contribute to background noise in fluorescent assays.
  • Validation of Experimental Conditions: By using an IgM isotype control, researchers can confirm that any observed biological effects are due to specific interactions rather than artifacts from assay conditions or reagents.
  • Accurate Data Interpretation: Incorporating IgM controls enhances the reliability of data interpretation, ensuring that conclusions drawn from experiments reflect true biological phenomena.

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RUOCE / IVD
  • Unconjugated 495
  • PE 64
  • FITC 46
  • APC 33
  • Biotin 28
  • PerCp 20
  • PE/Cy7 14
  • Alexa Fluor 488 13
  • PE/Cy5 12
  • APC/Cy5.5 10
  • APC/Cy7 10
  • HRP 9
  • PE/Cy5.5 9
  • PerCP/Cy5.5 9
  • Alexa Fluor 647 8
  • azide free 7
  • low endotoxin 7
  • Alexa Fluor 350 5
  • Alexa Fluor 555 5
  • Alexa Fluor 750 5
  • Cy3 5
  • Cy5 5
  • Cy5.5 5
  • Cy7 5
  • Low Endotoxin/Azide Free 4
  • PE-Cy5 2
  • PE-Cy7 2
  • SPRD 2
  • R-PE 1
  • Red 1
  • TRITC 1
  • mouse 22
  • human 17
  • rat 7
  • pig 3
  • rabbit 3
  • cat 2
  • horse 2
  • plant 2
  • chicken 1
  • dog 1
  • ferret 1
  • sheep 1
  • mouse 566
  • rat 330
  • human 20
  • rabbit 10
  • cat 2
  • donkey 2
  • pig 2
  • chicken 1
  • dog 1
  • ferret 1
  • guinea pig 1
  • sheep 1
  • Control isotype 1003
  • FC 825
  • ELISA 87
  • IF 18
  • FLISA 11
  • in-vivo 10
  • IHC 8
  • WB 8
  • IP 4
  • Microscopy 2
  • MM-30 219
  • RTK2118 185
  • 6F8-E10 100
  • Polyclonal 82
  • Monoclonal 42
  • 11E10 27
  • NIP/M-2 20
  • PFR-03 15
  • 110000000000 4
  • 7C2C6C2 4
  • ES26-13D3.4 3
  • SAA0186 3
  • SPE-7 3
  • 7E10 2
  • B11/7 2
  • GC323 2
  • IS5-20C4 2
  • SAA0185 2
  • eBRM 2
  • monoclonal 2
  • 3H2447 1
  • B1-8 1
  • C1.18.4 1
  • COLIS52A2 1
  • HEL D1.3 1
  • MK02 1
  • MMK 1
  • MML 1
  • No.MK02 1
  • polyclonal 1
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Description
Cond.
Price Bef. VAT
M079-3
 100ul 
AM08215RC7-N
 100ug 
AM08215LE-N
 500ug 
AM08215BT-N
 500ug 
AM08215AC-N
 100ug 
AM08215RP-N
 100ug 
AM08215FC-N
 500ug 
AM08215PU-N
 500ug 
AM08206FC-N
 100Tests 
AM08206RC7-N
 100Tests 
AM08206LE-N
 500ug 
AM08206PU-N
 1mg 
AM08206BT-N
 500ug 
AM03111FC-N
 100ug 
GTX03790-500ug
 500ug 
AM03111PU-N
 100ug 
AM08206RP-N
 100Tests 
AM08206AC-N
 100Tests 
GTX76403-100test
 100test 
GTX35038-50μg
 50μg 
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    10