In-Depth Analysis of Most Used ELISA Biomarker Kits in Research
ELISA kits are among the most commonly used tools in laboratories today. This report explores the most popular kits and their applications.
Enzyme-Linked Immunosorbent Assay (ELISA) kits are essential in detecting and quantifying biomarkers across clinical diagnostics, research, and quality control. The market for these kits is expanding rapidly due to rising incidences of chronic and infectious diseases, an increased emphasis on early diagnosis, and continuous technological innovations such as high-sensitivity and multiplexing capabilities. Global market estimates project robust growth with major contributions from North America and rapid expansion in the Asia-Pacific region.
The global enzyme immunoassay market was valued at approximately USD 17.67 billion in 2023 and is anticipated to grow at a compound annual growth rate (CAGR) of 3.9% between 2024 and 2030 (Figure 1). This growth is driven by several factors, including the rising need for automated diagnostic testing, the increasing incidence of chronic and infectious diseases, and heightened awareness of diagnostic services. Furthermore, the expanding elderly population and rising healthcare spending are expected to contribute significantly to market expansion over the coming years. By 2050, the World Health Organization projects that the global population aged 60 and above will double to 2.1 billion, while those aged 80 or older are expected to triple from 2020 levels, reaching 426 million by 2050 (Grand View Research, 2023).
Figure 1: Enzyme immunoassay market size, by product, 2020-2030 (USD Billion)
Applications of ELISA Biomarker Kits
ELISA is a biochemical assay that uses enzyme-labeled antibodies to detect and quantify proteins, hormones, and other molecules in biological samples. Owing to its high sensitivity and specificity, ELISA is widely adopted in:
Clinical Diagnostics: For early detection and monitoring of diseases like HIV, hepatitis, and cancer.
Immunology: Measuring cytokine levels (e.g., IL-6, TNF-α) in autoimmune and inflammatory conditions.
Drug Discovery: Biomarker validation in preclinical and clinical research.
Environmental & Food Safety: Detection of contaminants, toxins, and allergens.
Most Cited ELISA Kits in Research
The following ELISA kits have been among the most frequently referenced in the scientific literature:
| Research Area | Common Biomarkers Detected | Common Applications |
| Cancer Research | VEGF, IL-6, TNF-α | Tumor progression, immunotherapy response, angiogenesis |
| Cardiovascular Research | CRP, Troponins, BNP | Cardiovascular diseases, myocardial infarction, heart failure |
| Infectious Disease Research | HIV, SARS-CoV-2 Spike Protein | Early diagnosis, viral load quantification, vaccine research |
| Endocrinology Research | Cortisol, Insulin, Prolactin | Hormonal imbalance, metabolic disorders, stress responses |
| Immunology Research | IL-1β, IL-10, TNF-α | Inflammation, immune response, autoimmune diseases |
ELISA kits remain indispensable tools in scientific research, with a broad range of applications across multiple fields. The most frequently cited ELISA kits focus on biomarkers like cytokines (e.g., IL-6, TNF-α), hormones (e.g., insulin, cortisol), and cardiovascular markers (e.g., CRP, troponins). Trends suggest a growing interest in high-sensitivity and multiplex kits, driven by the need for more efficient and precise diagnostic tools.
As scientific research continues to evolve, ELISA kits will play a central role in understanding disease mechanisms, developing treatments, and enabling early diagnosis in various fields, from oncology to infectious diseases.
Enzyme-Linked Immunosorbent Assay (ELISA) kits
References
Grand View Research (2023). Enzyme-Linked Immunosorbent Assay Market Size, Share, Trends & Analysis Report.