Run better your RT-PCR for free, Test our Marathon RT!

Run better your RT-PCR for free, Test our Marathon RT!

 

 

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Offer Valid until December 31st, 2024


We are pleased to introduce the UltraMarathonRT (uMRT) offerings: the uMRT Reverse Transcriptase and the uMRT Template Switching Kit. These next-generation reverse transcriptases deliver enhanced visibility into low-abundance and long, structured RNAs, along with their diverse isoforms. Engineered as a highly optimized group II intron RT, UltraMarathonRT (uMRT) significantly outperforms conventional MMLV and AMV reverse transcriptases, setting a new standard in RNA research.

Take Advantage of Our Limited-Time Offer: Try These Products for Free!


 

The uMRT is engineered to provide greater visibility into low-abundance and highly structured RNAs, enabling critical applications in:

 

Discovery Research: Reveal intricate gene expression and regulation dynamics.

 

Cell & Gene Therapy: Enhance quality control in next-generation cell, gene, and RNA therapy vaccine programs.

 

Diagnostics & Surveillance: Support diagnostics for oncology, rare inherited diseases, and infectious disease


Key Benefits 

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Ultra-Processive cDNA Synthesis: Achieves high-fidelity, end-to-end synthesis of entire transcripts in a single pass, including 30 kb viral genomes.

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Unique Intrinsic Helicase Activity: Rapidly unwinds complex RNA structures without the need for heating, preserving sample integrity.

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Proprietary BOOST Buffer: Dramatically improves cDNA synthesis from samples as low as 1 pg compared to conventional enzymes.

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Optimal Performance at Ambient Temperatures (20–40°C): Prevents degradation of delicate RNA samples, ensuring reliable results.


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Identify more genes
Changing the standard RT to uMRT, enabled the identification of 25% more genes
 

More consistent coverage from 5' to 3' ends
uMRT significantly reduces the problem of 3’ bias.

uMRT Reverse Transcriptase

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  • UltraMarathonRTTM Reverse Transcriptase Kit is designed to meet the evolving needs of the RNA research community.
  • It is an ultra-processive reverse transcriptase that creates cDNAs from any type of RNA in a single pass, including long and highly structured templates.
  • Operates optimally at ambient temperatures (20-42ºC), eliminating the need for heating the RT reaction, which helps preserve the integrity of RNA samples.
  • Suitable for gene expression, RT-PCR, qRT-PCR, and other first strand cDNA synthesis applications.
  • Supports RNA input as low as 0.1 pg.

View Products


uMRT Template Switching Kit

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  • UltraMarathonRTTM Template Switching Kit is ideal for library prep in RNA-seq applications.
  • Features consistent and efficient terminal transferase activity, enabling use in applications where template switching is preferred.
  • Capable of creating cDNA from any RNA: long or short, highly structured, or difficult transcripts of any abundance.
  • When used with the Template Switching Oligo (TSO), it allows for the creation of full-length cDNAs while adding appropriate sequencing adapters.
  • Reduces cDNA library bias in sequencing.
  • Suitable for bulk sequencing library preparation and low abundant RNA samples in long-read sequencing, SMART-seq, and RACE applications.
  • Supports RNA input from 0.1 ng – 20 ng.

View Products


Don’t miss out on this chance to elevate your RNA research!

Click the links below to request your free trial today


Request your Free trial


Learn more about Reverse Transcriptase


 

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