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Reagents and instruments for immunology, cell biology and molecular biology.

Anti-NALCN Antibody FL550 Conjugate

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Cat# 75-220-FL550

Size : 200uL

Contact local distributor :

Phone : +1 850 650 7790

Brand : Antibodies Incorporated

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Contact local distributor :

Phone : +1 850 650 7790

SKU: 75-220-FL550

Product Details

Target

NALCN

Target Description

Sodium Leak Channel, Non-Selective is encoded by the gene NALCN. NALCN is a member of the cation-nonselective channel family. NALCN is a voltage-independent, cation-nonselective channel which is permeable to sodium, potassium, and calcium ions. NALCN regulates the resting membrane potential and controls neuronal excitability. NALCN is expressed in the brain, heart, and pancreas. Diseases associated with NALCN include Congenital Contractures of the Limbs and Face, Hypotonia, and Developmental Delay and Hypotonia, Infantile, with Psychomotor Retardation and Characteristic Facies 1.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N185/7

Isotype

IgG1

Applications

ICC

Host Species

Mouse

Gene Name

Nalcn Nca Rb21 Vgcnl1

Molecular Weight

200 kDa

Antigen

Fusion protein amino acids 1659-1738 (cytoplasmic C-terminus) of rat NALCN (accession number Q6Q760) produced recombinantly in E. Coli

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2939809

Storage

Aliquot and store at -8% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL550 Ex: 550 nm, Em: 575 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Sodium leak channel non-selective protein (Four domain-type voltage-gated ion channel alpha-1 subunit) (Rb21-channel) (Voltage gated channel-like protein 1)

UniProt Details

UniProt (Human): Q8IZF0
UniProt (Immunogen Species): Q6Q760

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