Quimigen Portugal > B2M Antibody - N-terminal region : FITC
B2M Antibody - N-terminal region : FITC
Brand : Aviva Systems Biology
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Datasheets/Manuals | Printable datasheet for anti-B2M (ARP56555_P050-FITC) antibody |
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Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep |
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Product Format | Liquid. Purified antibody supplied in 1x PBS buffer. |
Clonality | Polyclonal |
Host | Rabbit |
Conjugation | FITC: Fluorescein Isothiocyanate |
Application | WB |
Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human B2M |
Purification | Affinity Purified |
Predicted Homology Based on Immunogen Sequence | Cow: 79%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 93%; Sheep: 83% |
Peptide Sequence | Synthetic peptide located within the following region: MSRSVALAVLALLSLSGLEAIQRTPKIQVYSRHPAENGKSNFLNCYVSGF |
Concentration | 0.5 mg/ml |
Blocking Peptide | For anti-B2M (ARP56555_P050-FITC) antibody is Catalog # AAP56555 (Previous Catalog # AAPP39214) |
Reference | Platt,G.W., (2008) J. Mol. Biol. 378 (1), 251-263 |
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Gene Symbol | B2M |
Gene Full Name | Beta-2-microglobulin |
Alias Symbols | IMD43 |
NCBI Gene Id | 567 |
Protein Name | Beta-2-microglobulin |
Description of Target | This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fib |
Uniprot ID | P61769 |
Protein Accession # | NP_004039 |
Nucleotide Accession # | NM_004048 |
Protein Size (# AA) | 119 |
Molecular Weight | 12kDa |
Protein Interactions | UBC; CRYAB; B2M; MAPK15; TAP2; HLA-A; HFE; HLA-B; TAPBP; TAP1; GRB2; LILRB1; PRSS23; FCGRT; CD1E; CD1D; CD1A; CD1B; CD8A; HLA-F; HLA-E; HLA-G; HLA-C; BAG6; CALR; A2M; |
Protein interactions
Name | # of Products |
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A2M | 261 |
B2M | 110 |
BAG6 | 225 |
CALR | 206 |
CD1A | 20 |
CD1B | 21 |
CD1D | 104 |
CD1E | 20 |
CD8A | 170 |
FCGRT | 41 |
GRB2 | 1020 |
HFE | 42 |
HLA-A | 105 |
HLA-B | 123 |
HLA-C | 93 |
HLA-E | 66 |
HLA-F | 27 |
HLA-G | 68 |
LILRB1 | 35 |
PRSS23 | 78 |
UBC | 7030 |
Biological pathways
Name | # of Products |
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Antigen processing and presentation of peptide antigen via MHC class I | 174 |
Interferon-gamma-mediated signaling pathway | 264 |
Regulation of defense response to virus by virus | 124 |
Regulation of immune response | 318 |
Viral reproduction | 431 |
Biological process
Name | # of Products |
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Antigen processing and presentation of exogenous peptide antigen via MHC class I | 67 |
Antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 61 |
Antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent | 9 |
Antigen processing and presentation of peptide antigen via MHC class I | 83 |
Cytokine-mediated signaling pathway | 229 |
Immune response | 404 |
Interferon-gamma-mediated signaling pathway | 61 |
Regulation of defense response to virus by virus | 24 |
Regulation of immune response | 89 |
Viral reproduction | 279 |
Cellular components
Name | # of Products |
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Early endosome lumen | 3 |
Early endosome membrane | 51 |
Endoplasmic reticulum lumen | 87 |
ER to Golgi transport vesicle membrane | 20 |
Extracellular region | 1573 |
Golgi membrane | 308 |
MHC class I protein complex | 19 |
Phagocytic vesicle membrane | 19 |
Plasma membrane | 2678 |
Protein function
Name | # of Products |
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Protein binding | 12191 |
Diseases
Name | # of Products |
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Amyloidosis | 223 |
Disease mutation | 5332 |
- B2M Antibody - N-terminal region (ARP56555_P050)Catalog #: ARP56555_P050Species Tested: HumanApplication: WBFormat: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
- Recombinant Human Beta 2 Microglobulin Protein (OPPA01252)Catalog #: OPPA01252Format: The protein was lyophilized from a concentrated solution (1mg/ml) containing PBS (pH 7.4) and 0.05% NaN3. Physical appearance: Sterile Filtered White lyophilized (freeze-dried) powder.Size: 10UG
- B2M Human - Human Beta 2 Microglobulin Protein (OPPA01430)Catalog #: OPPA01430Format: Lyophilized from 0.02M NH4HCO3.
Physical appearance: Sterile Filtered White lyophilized (freeze-dried) powder.Size: 200UG - beta 2-Microglobulin ELISA Kit (Human) (OKIA00054)Catalog #: OKIA00054Application: ELISAKit Range: 3.125 ng/ml - 100 ng/mlSensitivity: 0.822 ng/mlFormat: In SolutionSize: 96W
- beta-2 Microglobulin ELISA Kit (Rat) (OKIA00134)Catalog #: OKIA00134Application: ELISAKit Range: 0.156 ng/ml - 5 ng/mlSensitivity: 0.835 ng/mlFormat: In SolutionSize: 96W