CLK4 antibody - N-terminal region
Cat# ARP30645_P050
Size : 100ul
Brand : Aviva Systems Biology
Datasheets/Manuals | Printable datasheet for anti-CLK4 (ARP30645_P050) antibody |
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Publications | Eisenreich, A. et al. Regulation of pro-angiogenic tissue factor expression in hypoxia-induced human lung cancer cells. Oncol. Rep. 30, 462-70 (2013). 236044721$s> |
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Tested Species Reactivity | Human |
Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast |
Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Clonality | Polyclonal |
Host | Rabbit |
Application | WB |
Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human CLK4 |
Purification | Affinity Purified |
Predicted Homology Based on Immunogen Sequence | Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 93%; Yeast: 91% |
Peptide Sequence | Synthetic peptide located within the following region: RSRRSSPKRKRNRHCSSHQSRSKSHRRKRSRSIEDDEEGHLICQSGDVLR |
Concentration | 0.5 mg/ml |
Blocking Peptide | For anti-CLK4 (ARP30645_P050) antibody is Catalog # AAP30645 (Previous Catalog # AAPP01302) |
Gene Symbol | CLK4 |
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Gene Full Name | CDC-like kinase 4 |
Alias Symbols | DKFZp686A20267 |
NCBI Gene Id | 57396 |
Protein Name | Dual specificity protein kinase CLK4 |
Description of Target | The protein encoded by this gene belongs to the CDC2-like protein kinase (CLK) family. This protein kinase can interact with and phosphorylate the serine- and arginine-rich (SR) proteins, which are known to play an important role in the formation of spliceosomes, and thus may be involved in the regulation of alternative splicing. Studies in the Israeli sand rat Psammomys obesus suggested that the ubiquitin-like 5 (UBL5/BEACON), a highly conserved ubiquitin-like protein, may interact with and regulate the activity of this kinase. Multiple alternatively spliced transcript variants have been observed, but the full-length natures of which have not yet been determined. |
Uniprot ID | Q9HAZ1 |
Protein Accession # | NP_065717 |
Nucleotide Accession # | NM_020666 |
Protein Size (# AA) | 481 |
Molecular Weight | 57 |
Protein Interactions | KPNA1; KRTAP10-3; KRTAP10-8; KRTAP10-9; KRTAP10-7; CLK4; SRRM2; AHCYL2; SUB1; RASA4; SRPK1; RNF181; CLASRP; UBL5; HSPB2; |
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What is the species homology for "CLK4 Antibody - N-terminal region (ARP30645_P050)"?
The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast".
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How long will it take to receive "CLK4 Antibody - N-terminal region (ARP30645_P050)"?
This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".
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What buffer format is "CLK4 Antibody - N-terminal region (ARP30645_P050)" provided in?
This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "CLK4 Antibody - N-terminal region (ARP30645_P050)"?
This target may also be called "DKFZp686A20267" in publications.
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What is the shipping cost for "CLK4 Antibody - N-terminal region (ARP30645_P050)"?
The shipping cost for this item is within the US. Please contact us for specific shipping for international orders.
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What is the guarantee for "CLK4 Antibody - N-terminal region (ARP30645_P050)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "CLK4 Antibody - N-terminal region (ARP30645_P050)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "57".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "CLK4 Antibody - N-terminal region (ARP30645_P050)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "CLK4"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "CLK4"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "CLK4"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "CLK4"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "CLK4"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "CLK4"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.