HAX1 (NM_006118) Human Untagged Clone
Cat# SC116339
Size : 10ug
Contact local distributor :
HAX1 (NM_006118) Human Untagged Clone
| Product Data | |
| Target Symbol | HAX1 |
|---|---|
| Synonyms | HCLSBP1; HS1BP1; SCN3 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data | Fully Sequenced ORF >OriGene ORF within SC116339 sequence for NM_006118 edited (data generated by NextGen Sequencing) ATGAGCCTCTTTGATCTCTTCCGGGGCTTTTTCGGCTTTCCTGGACCTCGGAGCCACAGA GATCCCTTTTTTGGAGGGATGACTCGAGATGAAGATGATGATGAGGAAGAAGAAGAAGAA GGGGGCTCATGGGGCCGTGGGAACCCAAGGTTCCATAGTCCTCAGCACCCCCCTGAGGAA TTTGGCTTCGGCTTCAGCTTCAGCCCAGGAGGAGGGATACGTTTCCACGATAACTTCGGC TTTGATGACCTAGTACGAGATTTCAATAGCATCTTCAGCGATATGGGGGCCTGGACCTTG CCTTCCCATCCTCCTGAACTTCCAGGTCCTGAGTCAGAGACACCTGGTGAGAGACTACGG GAGGGACAGACACTTCGGGACTCAATGCTTAAGTATCCAGATAGTCACCAGCCCAGGATC TTTGGGGGGGTCTTGGAGAGTGATGCAAGAAGTGAATCCCCCCAACCAGCACCAGACTGG GGCTCCCAGAGGCCATTTCATAGGTTTGATGATGTATGGCCTATGGACCCCCATCCTAGA ACCAGAGAGGACAATGATCTTGATTCCCAGGTTTCCCAGGAGGGTCTTGGCCCGGTTCTA CAGCCCCAGCCCAAATCCTATTTCAAGAGCATCTCTGTGACCAAGATCACTAAACCAGAT GGGATAGTGGAGGAGCGCCGGACTGTGGTGGACAGTGAGGGCCGGACAGAGACTACAGTA ACCCGACACGAAGCAGATAGCAGTCCTAGGGGTGATCCAGAATCACCAAGACCTCCAGCC CTGGATGATGCCTTTTCCATCCTGGACTTATTCCTGGGACGTTGGTTCCGGTCCCGGTAG Clone variation with respect to NM_006118.3 5' Read Nucleotide Sequence >OriGene 5' read for NM_006118 unedited ATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGAATTTCTCACAG GGCTGCGCAGGTTTCCCCCGTCTGCGAATGGACCACTGGAGGGGTTCAAAGGTTCGCGTC CCAGTACGGGAATGAGCCTCTTTGATCTCTTCCGGGGCTTTTTCGGCTTTCCTGGACCTC GGAGCCACAGAGATCCCTTTTTTGGAGGGATGACTCGAGATGAAGATGATGATGAGGAAG AAGAAGAAGAAGGGGGCTCATGGGGCCGTGGGAACCCAAGGTTCCATAGTCCTCAGCACC CCCCTGAGGAATTTGGCTTCGGCTTCAGCTTCAGCCCAGGAGGAGGGATACGTTTCCACG ATAACTTCGGCTTTGATGACCTAGTACGAGATTTCAATAGCATCTTCAGCGATATGGGGG CCTGGACCTTGCCTTCCCATCCTCCTGAACTTCCAGGTCCTGAGTCAGAGACACCTGGTG AGAGACTACGGGAGGGACAGACACTTCGGGACTCAATGCTTAAGTATCCAGATAGTCACC AGCCCAGGATCTTTGGGGGGGTCTTGGAGAGTGATGCAAGAAGTGAATCCCCCCAACCAG CACCAGACTGGGGCTCCCAGAGGCCATTTCATAGGTTTGATGATGTATGGCCTATGGACC CCCATCCTAGAACCAGAGAGGACANTGATCTTGATTCCCAGGTTTTCCAGGAGGGTCTTG GCCCGGTTCTACAGCCCCAGCCCAAATCCTATTTCAAGAGCATCTCTGTGACCAAGATCA CTAAACCAGATGGGATAGTGGAGGAGCGCCGGACTGTGGTTNACAGTTGAGGCCGGACAA GACTCAGTAACCCGACACGAGCAGATAC 3' Read Nucleotide Sequence >OriGene 3' read for NM_006118 unedited GGCCGCAATTTANAGTCGAGNTTTTTTTTTTTTTTTTTTTTTTTTTTTTTATTTTAAATA AAGGTTTTATTGGTCAGTTTGGGTGAGTGACAAACTGACATGGCCCCAGTTCACTATTCC ACATATCCAAGCCCCTGAGGTGGCAAGAGAAGCTAAGCTTATTAATGGTGGGCAATGGGT GAAAGGTGGAAAGGACTTGAAGGCCTCTGAGGGTTAACAAGGCTACCGGGACCGGAACCA ACGTCCCAGGAATAAGTCCAGGATGGAAAAGGCATCATCCAGGGCTGGAGGTCTTGGTGA TTCTGGATCACCCCTAGGACTGCTATCTGCTTCGTGTCGGGTTACTGTAGTCTCTGTCCG GCCCTCACTGTCCACCACAGTCCGGCGCTCCTCCACTATCCCATCTGGTTTAGTGATCTT GGTCACAGAGATGCTCTTGAAATAGGATTTGGGCTGGGGCTGTACAACCGGGCCAAGACC CTCCTGGGAAACCTGGGAATCAAGATCATTGTCCTCTCTGCGTCTAGGATGGGGGTCCAT AGGCCATACCTTATCAAACCTATGAAATGGCCTCTGGGACCCCACTCTGGCGCTGGTTGG GGGGATTCACCTTTTGCATCACTCTCCAAGACCCCCCAAAAATCCTGGGGCTGCGACTAT TTGGATACTTAAACCCTTGGGTCCCCAAGCGGCTGCCCCTTCCCCGATCCCCTCACCAGG TGCCCCTGCCTCAGCCCTCCACATCTCCGAGGATGGGAAGGCAAGGTCCAGCCCCCATCT TCTCAACATCCTTCTGAAACCTCCTCCATGTCCATCACCGCCCCAGCCTTCGGGGAAACC GTCCCCTTTCTCCGGGCGTTAAACTTGACCCTAACCCTCATCCTCCACGGCGGGGCCGCA GATTCGTTCATCTTCGGTCCCACTGGACACTTAGACCCCCCCTTTTTTTTCTCCCTCCAC CCTTTTNTTGTCCGCGNTCCCCCCAGACGGCACTCTTGGGT |
| Restriction Sites | NotI-NotI Plasmid Map |
| ACCN | NM_006118 |
| Insert Size | 1090 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_006118.3, NP_006109.2 |
| RefSeq Size | 1196 bp |
| RefSeq ORF | 840 bp |
| Locus ID | 10456 |
| UniProt ID | O00165 |
| Cytogenetics | 1q21.3 |
| Summary | The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). |