Human Phospholipase D1 (PLD1) activation kit by CRISPRa

Cat# GA103597

Size : 1kit

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Human Phospholipase D1 (PLD1) activation kit by CRISPRa

Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PLD1
Locus ID 5337
Components

GA103597G1, Phospholipase D1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103597G2, Phospholipase D1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103597G3, Phospholipase D1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001130081, NM_002662
UniProt ID Q13393
Synonyms Phoshpolipase D gene 1 probably with two splicing variants A and B; phospholipase D1; phospholipase D gene 1, probably with two splicing variants A and B; Pld1a; Pld1b; Plda; Pldb
Summary This gene encodes a phosphatidylcholine-specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking. Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties. [provided by RefSeq, Sep 2011]
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SKU Description Size
KN409070 PLD1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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