Marco Antibody

Cat# OASA05707

Size : 25ug

Brand : Aviva Systems Biology

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Marco Antibody (OASA05707)

Datasheets/ManualsPrintable datasheet for Marco Antibody (OASA05707)
Product Info
Predicted Species ReactivityMouse
Product FormatLiquid. Phosphate buffered saline
ClonalityMonoclonal
CloneED31
IsotypeIgG1
HostRat
ApplicationIF, IP
Additional InformationFusion Partners: Spleen cells from immunised rats were fused with cells of the mouse SP2/0 myeloma cell line.
Reconstitution and Storage-20°C
ImmunogenCHO cells expressing mouse MARCO.
PurificationProtein G Purified
Concentration1 mg/ml
SpecificityRat anti Mouse MARCO antibody, clone ED31 recognizes the murine cell surface antigen designated MARCO (Macrophage receptor with collagenous structure), which is a member of the class A scavenger receptor family.
Application InfoIHC-F: 1/200 - 1/400
Optimal dilutions should be determined by the end user.
Gene SymbolMarco
Alias SymbolsSc, Ly112, Scara2, AI323439
NCBI Gene Id17167
Protein NameMacrophage receptor MARCO
Description of TargetMARCO is expressed by distinct populations of macrophages in the spleen and lymph nodes, but is rapidly induced on macrophages in other tissues (e.g. Liver Kupffer cells) during infection or LPS treatment. Rat anti Mouse MARCO antibody, clone ED31 binds to the C-terminal cysteine rich domain of MARCO, and has been shown to block ligand binding.
Uniprot IDQ60754
Protein Accession #NP_034896.1