Quimigen Portugal > MFN1 Antibody - middle region
MFN1 Antibody - middle region
Brand : Aviva Systems Biology
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Datasheets/Manuals | Printable datasheet for anti-MFN1 (ARP57702_P050) antibody |
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Publications | Bonala, S. et al. Pid1 induces insulin resistance in both human and mouse skeletal muscle during obesity. Mol. Endocrinol. 27, 1518-35 (2013). 239279301 maintains mitochondrial structure and contributes to stress-induced permeability transition in cardiac myocytes. Mol. Cell. Biol. 31, 1309-28 (2011). 212453731x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. | ||||||
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Clonality | Polyclonal | ||||||
Host | Rabbit | ||||||
Application | WB | ||||||
Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. | ||||||
Immunogen | The immunogen is a synthetic peptide directed towards the middle region of human MFN1 | ||||||
Purification | Affinity Purified | ||||||
Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Horse: 86%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 100%; Rat: 100% | ||||||
Peptide Sequence | Synthetic peptide located within the following region: QVDITQKQLEEEIARLPKEIDQLEKIQNNSKLLRNKAVQLENELENFTKQ | ||||||
Concentration | 0.5 mg/ml | ||||||
Blocking Peptide | For anti-MFN1 (ARP57702_P050) antibody is Catalog # AAP57702 (Previous Catalog # AAPP42948) | ||||||
Enhanced Validation |
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Gene Symbol | MFN1 |
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Gene Full Name | Mitofusin 1 |
Alias Symbols | hfzo1, hfzo2 |
NCBI Gene Id | 55669 |
Protein Name | Mitofusin-1 |
Description of Target | The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting. |
Uniprot ID | Q8R4Z9 |
Protein Accession # | NP_284941 |
Nucleotide Accession # | NM_033540 |
Protein Size (# AA) | 741 |
Molecular Weight | 84 kDa |
Protein Interactions | PARK2; MARCH5; UBC; TER94; MAVS; CCNB1; ILF2; BAK1; |
Protein interactions
Name | # of Products |
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BAK1 | 70 |
MARCH5 | 31 |
PARK2 | 202 |
Biological pathways
Name | # of Products |
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Mitochondrial fusion | 10 |
Biological process
Name | # of Products |
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GTP catabolic process | 157 |
Mitochondrial fusion | 9 |
Cellular components
Name | # of Products |
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Cytoplasm | 4549 |
Integral to membrane | 2793 |
Membrane | 2769 |
Mitochondrial outer membrane | 89 |
Mitochondrion | 1154 |
Protein function
Name | # of Products |
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GTP binding | 556 |
GTPase activity | 362 |
Hydrolase activity | 1739 |
Nucleotide binding | 3928 |
- MFN1 Antibody - N-terminal region (OABB01708)Catalog #: OABB01708Clone: PolyclonalSpecies Tested: Human, Mouse, RatApplication: WBFormat: Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.Size: 100UG
- MFN1 Recombinant Protein (OPCD00818)Catalog #: OPCD00818Conjugation: UnconjugatedApplication: Ctrl (+), SDS-PAGE, WBFormat: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
- MFN1 ELISA Kit (Human) (OKCD00342)Catalog #: OKCD00342Application: ELISA-SandwichKit Range: 0.156-10ng/mLSensitivity: < 0.059 ng/mLSize: 96WELLS
- MFN1 Antibody - N-terminal region (ARP57701_P050)Catalog #: ARP57701_P050Species Tested: Human, MouseApplication: WBFormat: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.