CD40 Unconjugated
Catalog #
Size
Lymphocyte-gated PBMCs stained with unconjugated CD40 followed by goat anti-mouse IgG Alexa Fluor 488 (RED); Lymphocyte-gated PBMCs stained with unconjugated mouse IgG1 followed by goat anti-mouse IgG Alexa Fluor 488 (BLUE).
| Conjugation | Unconjugated |
|---|---|
| Antigen | CD40 |
| Clone | G28-5 |
| Isotype | IgG1, k |
| Applications | FC |
| Reactivity | Baboon, Cynomolgus monkey, Human, Rhesus |
| Host | Mouse |
| Clonality | Monoclonal |
| Primary/Secondary | Primary |
| Storage | 2-8°C |
| Status | RUO |
Description:
The clone G28-5 is specific for CD40 B cell surface antigen. It is a 48 kD type I glycoprotein and a member of the tumor necrosis factor receptor superfamily. CD40 is the receptor for CD40 ligand (CD40L), a molecule predominantly expressed by activated CD4+ T cells. The CD40 on B cells and CD40L (CD154) on activated helper T cells are co-stimulatory molecules whose interaction is required for the proliferation and immunoglobulin (Ig) class switching of antigen-activated B cells.
The clone G28-5 is specific for CD40 B cell surface antigen. It is a 48 kD type I glycoprotein and a member of the tumor necrosis factor receptor superfamily. CD40 is the receptor for CD40 ligand (CD40L), a molecule predominantly expressed by activated CD4+ T cells. The CD40 on B cells and CD40L (CD154) on activated helper T cells are co-stimulatory molecules whose interaction is required for the proliferation and immunoglobulin (Ig) class switching of antigen-activated B cells.