Mouse Anti-Human CD3-UNLB
Cat# 9515-01
Size : 0.1mg
Brand : Southern Biotech
Contact local distributor :
Phone : +1 850 650 7790
| Clone | UCHT1 |
|---|---|
| Isotype | Mouse (BALB/c) IgG1κ |
| Isotype Control | Mouse IgG1-UNLB (15H6) |
| Specificity | Human CD3 |
| Alternative Names | CD3ε, T3E, TCRE, Leu-4, T3 |
| Description | CD3, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). CD3 is expressed on 70-80% of normal peripheral blood lymphocytes and on 10-20% of thymocytes. It plays a major role in signaling during antigen recognition, leading to T cell activation. The monoclonal antibody UCHT1 reacts with the 20 kDa ε chain of the CD3/TCR complex. |
| Immunogen | Human peripheral blood lymphocytes from a patient with Sézary's syndrome and infant thymocytes |
| Conjugate | UNLB (Unconjugated) |
| Buffer Formulation | Borate buffered saline, pH 8.2 |
| Clonality | Monoclonal |
| Concentration | 0.1 mg/mL |
| Volume | 1.0 mL |
| Recommended Storage | 2-8°C |
| Applications | Flow Cytometry – Quality tested 1,6-11 Immunohistochemistry-Frozen Sections – Reported in literature 4,5 Immunohistochemistry-Paraffin Sections – Reported in literature 5 Immunocytochemistry – Reported in literature 1 Immunoprecipitation – Reported in literature 2 Western Blot – Reported in literature 3 Activation – Reported in literature 1,2 Blocking – Reported in literature 2 |
| RRID Number | AB_2796826 |
| Gene ID | 916 (Human) |
| Gene ID Symbol | CD3E (Human) |
| Gene ID Aliases | T3E; TCRE; IMD18 |
| UniProt ID | P07766 (Human |
| UniProt Name | CD3E_HUMAN (Human) |
Documentation
Technical Bulletin Safety Datasheet
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- 2. Burns GF, Boyd AW, Beverley PC. Two monoclonal anti-human T lymphocyte antibodies have similar biologic effects and recognize the same cell surface antigen. J Immunol. 1982;129:1451-7. (IP, Activ, Block)
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