Mouse IL-28B ELISA
Cat# DIY1622M-003
Size : 1Set
Brand : Kingfisher Biotech
Contact local distributor :
Phone : +1 850 650 7790
Mouse IL-28B ELISA Data
Mouse IL-28B ELISA Kit Components
| Component | Usage | Quantity | Catalog # |
| Anti-Mouse IL-28B Polyclonal Antibody | Capture Antibody | 100 µg | KP1620M-100 |
| Biotinylated Anti-Mouse IL-28B Polyclonal Antibody | Detection Antibody | 50 µg | KPB1621M-050 |
| Mouse IL-28B Recombinant Protein | Standard | 5 µg | RP1399M-005 |
Mouse IL-28B ELISA Specifications
The Mouse IL-28B Do-It-Yourself ELISA contains capture antibody, recombinant protein standard, and detection antibody for development of a Mouse ELISA. The antibodies have been determined to function in an ELISA with the standard provided. Optimal buffers, concentrations, incubation times, incubation temperatures, and methods for the ELISA have not been determined. A working knowledge of ELISA is strongly recommended. The quantities of components provided are not matched. Components may also be purchased separately.
For additional tips and techniques to ensure a successful ELISA, check out our ELISA Technical Guide.
IL-28B Background
IL-28B, IL-28A, and IL-29 are three closely related IFN-lambda cytokines that can be induced by viral infection that induce signaling through the Jak/STAT pathway. IL-28B, and other IFN-lambda cytokines, are well established as having several antiviral and anti-cancer activities. IFN-lambda, restricts virus from spreading into the brain and plays a major role in chronic viral infections found in the gastrointestinal tract. IL-28B, like other IFN-lambda cytokines, modulates innate and adaptive immunity, autoimmunity, and tumor progression. Unlike type I IFNs, which are able to stimulate most cell types, IL-28B, along with the other IFN-lambda cytokines, stimulation appears to be limited to dendritic cells and some tumor cell lines. Due to the affect IL-28B has on the adaptive immune system, it has gained much interest as an immunotherapeutic agent for treatment of allergic asthma. The IL-28 cytokines control T cell responses in vivo through the modulation of lung CD11c(+) DC function in experimental allergic asthma animal models. IFN-lambda cytokines, including IL-28B, have been shown to interact with a heterodimeric, class II cytokine receptor that consists of the IL-10 receptor, beta (IL-10RB) and the IL-28 receptor, alpha (IL-28RA) subunits. The promiscuous IL-10RB subunit is also common to IFN-alpha/beta family members, but the IL-28RA subunit is specific for the IFN-lambda cytokines, IL-28B, IL-28A, and IL-29.
Alternate Names - Interleukin 28B, IFNL3