Mouse Monoclonal Anti-Actin Smooth Muscle (Leiomyosarcoma Marker) (Clone 1A4; same as asm-1)
Cat# 24-59-MSM1-100ul
Size : 100ul
Brand : American Research Products
Contact local distributor :
Phone : +1 850 650 7790
Anti-Actin, Smooth Muscle (Leiomyosarcoma Marker), Monoclonal Antibody
| Product Name | Anti-Actin, Smooth Muscle (Leiomyosarcoma Marker), Monoclonal Antibody |
|---|---|
| Description | Actin is a major component of the cytoskeleton and is present in most cell types. This monoclonal antibody is highly specific to actin from smooth muscles. Its epitope lies in the first four N-terminal amino acids. This monoclonal antibody does not stain cardiac or skeletal muscle; however, it does stain myofibroblasts and myoepithelial cells. This antibody could be used together with anti-muscle specific actin and myogenin in making a diagnosis of smooth muscle and skeletal muscle tumors. In most cases of rhabdomyosarcoma, this antibody yields negative results whereas anti-muscle specific actin and myogenin are positive. Leiomyosarcomas are positive only with anti-muscle specific actin and anti-smooth muscle actin and are negative with anti-myogenin. |
| Synonyms | ACTA2, Actin Alpha 2 Smooth Muscle Aorta, Actin Aortic Smooth Muscle, Actin Vascular Smooth Muscle, ACTSA, ACTVS, Alpha 2 Actin, Alpha Actin 2, Alpha Cardiac Actin, Alpha Smooth Muscle, Alpha-actin-2, Aortic Smooth Muscle, ASMA, Cell Growth-inhibiting Gene 46 Protein, Growth Inhibiting Gene 46 |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 1A4; same as asm-1 |
| Immunogen | N-Terminal decapeptide of alpha smooth muscle isoform of actin and conjugated to KLH. |
| Isotype | IgG2a, kappa |
| Reactivity | Gallus, Bovine, Canine, Feline, Goat, Guinea Pig, Human, Mouse, Porcine, Primate, Rabbit, Rat, Sheep |
| Applications | FC, IF, IHC |
| Form | 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Gene Id | 59 |
| Uniprot | P62736 |
| Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
| References | Skalli O et. al. Journal of Cell Biology, 1986, 103:2787-96. |
| Supplier | ARP |
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