OGG1 Protein

Cat# OPPA02473

Size : 5ug

Brand : Aviva Systems Biology

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Datasheets/ManualsPrintable datasheet for OPPA02473
Product Info
Predicted Species ReactivityHuman
Product Format0.5mg/ml solution containing 20mM Tris buffer pH-8, 0.1M NaCl and 40% Glycerol. Physical appearance: Sterile filtered colorless solution.
HostE. Coli
::Product Introduction: OGG1 is a DNA glycosylase enzyme which takes part in base excision repair. OGG1 protein is the main enzyme accountable for the excision of 7,8-dihydro-8-oxoguanine (8-oxoG), a mutagenic base byproduct which arises as a result of exposure to reactive oxygen species (ROS). OGG1 shows beta lyase activity that nicks DNA 3'' to the lesion.
Product Description: OGG1 Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 368 amino acids (1-345 a.a.) and having a molecular mass of 41.2 kDa. The OGG1 is fused to 23 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Reconstitution and StorageOGG1 Human although stable at 4C for 1 week, should be stored below -18C. Please prevent freeze thaw cycles.
PurityGreater than 90.0% as determined by SDS-PAGE.
Peptide SequenceMGSSHHHHHH SSGLVPRGSH TGSMPARALL PRRMGHRTLA STPALWASIP CPRSELRLDL VLPSGQSFRW REQSPAHWSG VLADQVWTLTQTEEQLHCTV YRGDKSQASR PTPDELEAVR KYFQLDVTLA QLYHHWGSVD SHFQEVAQKF QGVRLLRQDP IECLFSFICS SNNNIARITGMVERLCQAFG PRLIQLDDVT YHGFPSLQAL AGPEVEAHLR KLGLGYRARY VSASARAILE EQGGLAWLQQ LRESSYEEAH KALCILPGVGTKVADCICLM ALDKPQAVPV DVHMWHIAQRDYSWHPTTSQ AKGPSPQTNK ELGNFFRSLW GPYAGWAQAV LFSADLRQCR HAQEPPAKRR.KGSKGPEG
Gene SymbolOGG1
Alias SymbolsHMMH, MUTM, OGH1, HOGG1
NCBI Gene Id4968
Protein NameN-glycosylase/DNA lyase
Description of TargetRecombinant Human 8-Oxoguanine DNA Glycosylase
Uniprot IDO15527
Protein Accession #NP_002533.1
Protein Size (# AA)Recombinant

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