Ovine IFN gamma Polyclonal Antibody - Biotinylated

Interferon-gamma (IFN-gamma) is a dimerized soluble cytokine that is the only member of the type II class of interferons. This interferon was originally called macrophage-activating factor, a term now used to describe a larger family of proteins to which IFN-gamma belongs. IFN-gamma, or type II interferon, is a cytokine that is critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Aberrant IFN-gamma expression is associated with a number of autoinflammatory and autoimmune diseases. The importance of IFN-gamma in the immune system stems in part from its ability to inhibit viral replication directly, but, most important, derives from its immunostimulatory and immunomodulatory effects. IFN-gamma is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.

Reactivity - ELISA
Bovine IFN gamma - Moderate
Canine IFN gamma - None
Caprine IFN gamma - Moderate
Chicken IFN gamma - None
Cynomolgus Monkey IFN gamma - None
Dolphin IFN gamma - Weak
Equine IFN gamma - None
Feline IFN gamma - None
Ferret IFN gamma - None
Human IFN gamma - None
Mouse IFN gamma - None
Ovine IFN gamma - Strong
Rabbit IFN gamma - None
Swine IFN gamma - None
Zebrafish IFN gamma 1-1 - None
Zebrafish IFN gamma 1-2 - None