PANC-1 cells
Cat# C0018010
Size : OneFrozenvial
Disease:
Epithelioid carcinoma of the pancreas
Origin:
established in 1972 from the ductal cells of a tumor located in the head of the pancreas of a 56-year-old man; the cells are described to be tumorigenic in nude-athymic mouse.
Species:
Homo sapiens Pancreas, duct Epithelial Adherent Chromosome studies indicate a modal number of 63 with 3 distinct marker chromosomes and a small ring chromosome. This is a hypertriploid human cell line. The modal chromosome number was 61, occurring in 32% of cells., However, cells with 63 chromosomes also occurred at a high frequency (22%). The rate of cells with higher ploidies was 8.5%. 2n = 46, hypertriploid Male, Caucasian, 56 years of age AddexBio-formulated DMEM (C0003-01) + 10% FBS When confluent using 0.25% trypsin or trypsin/EDTA, subculture at 1:2 to 1:4; feed cells 2 to 3 times weekly. Culture at 5% CO2, 37°C. Complete culture medium supplemented with 5% (v/v) DMSO I Bacteria: Negative Yeast: Negative Mycoplasma: Negative HIV: Negative Hepatitis B: Negative Hepatitis C: Negative Amelogenin: X CSF1PO: 10,12 D13S317: 11 D16S539: 11 D5S818: 11,13 D7S820: 8,10 THO1: 7,8 TPOX: 8,11 vWA: 15 Tissue:
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References for PANC-1 cells:
1. Lieber M, Mazzetta J, Nelson-Rees W, Kaplan M, Todaro G. Establishment of a continuous tumor-cell line (panc-1) from a human carcinoma of the exocrine pancreas. Int J Cancer. 1975 May 15;15(5):741-747. PMID: 1140870