Reagents and instruments for immunology, cell biology and molecular biology.
 
> Phosal 50 PG [774594-96-6]

Phosal 50 PG [774594-96-6]

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Cat# HY-Y1903-25mL

Size : 25mL

Brand : MedChemExpress

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Phosal 50 PG is a cosolvent (standardised phosphatidylcholine concentrate). Phosal 50 PG as a carrier for lipophilic compounds, can improve the absorption, efficacy and therapeutic index of the active ingredient.

For research use only. We do not sell to patients.

Phosal 50 PG Chemical Structure

Phosal 50 PG Chemical Structure

CAS No. : 774594-96-6

This product is a controlled substance and not for sale in your territory.

Based on 4 publication(s) in Google Scholar

Description

Phosal 50 PG is a cosolvent (standardised phosphatidylcholine concentrate). Phosal 50 PG as a carrier for lipophilic compounds, can improve the absorption, efficacy and therapeutic index of the active ingredient[1].

In Vivo

Phosal 50 PG is usually used as a cosolvent.
Navitoclax (HY-10087) (100 mg/kg, once a day for 21 days) is formulated in 10% ethanol, 30% polyethylene glycol 400, and 60% Phosal 50 PG and administered p.o. to mice[2].
A-1331852 (HY-19741) (25 mg/kg, daily for 10 days) is formulated in 2.5% DMSO, 10% ethanol, 27.5% PEG 300, and 60% Phosal 50 PG and administered p.o. to mice[3].
Venetoclax (HY-15531) (100 mg/kg, daily for 10 days) is formulated in 10% ethanol, 30% PEG 400, 60% Phosal 50 PG and administered p.o. to mice[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
CAS No.

774594-96-6
Appearance

Liquid (Density: 0.982 g/cm3)

Color

Light yellow to yellow

SMILES

[Phosal 50 PG]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light
Purity & Documentation

SDS (251 KB)

COA (242 KB)

Handling Instructions (2659 KB)
References

  • [1]. Khani S, et al. Improved oral bioavalability of mebudipine upon administration in PhytoSolve and Phosal-based formulation (PBF). AAPS PharmSciTech. 2014 Feb;15(1):96-102.  [Content Brief]

  • [1]. Khani S, et al. Improved oral bioavalability of mebudipine upon administration in PhytoSolve and Phosal-based formulation (PBF). AAPS PharmSciTech. 2014 Feb;15(1):96-102.

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Phosal 50 PG Related Classifications

  • Others
  • Others
  • Biochemical Assay Reagents

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Phosal 50 PG774594-96-6Biochemical Assay Reagentslipophilic compoundsabsorptionefficacytherapeutic indexphosphatidylcholineInhibitorinhibitorinhibit

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